| PI |
Institiute |
Research Title |
Year |
| |
|
|
|
| Lingyin Li |
Stanford University |
Chemical biology of anti-cancer innate immunity |
2017 |
| David Liu |
The Broad Institute of Harvard and MIT |
Expanding the scope of base editing |
2017 |
| Angela Koehler |
Massachusetts Institute of Technology |
Chemical probes for transcription |
2017 |
| Bridget Wagner |
The Broad Institute of Harvard and MIT |
Development of predictive signatures of drug toxicity and side effects using cell-based profiling |
2017 |
| Jonathan Watts |
University of Massachusetts - Worcester |
Development of next-generation antisense oligonucleotides for potent gene silencing in the lung |
2017 |
| |
|
|
|
| Michel Arkin |
University of California San Francisco |
Stabilizing 14-3-3 Protein-protein interactions with small molecules |
2018 |
| William Mobley |
University of California San Diego |
Selective Neuronal Delivery of ASOs Targeting APP |
2018 |
| Matthew Simon |
Yale University |
Transcriptome-wide discovery of small molecule binding sites in RNA |
2018 |
| Jack Taunton |
University of California San Francisco |
Chemoproteomic technology for the direct identification of druggable protein nucleophiles |
2018 |
| Christina Woo |
Harvard University |
Discovery of novel small molecule-protein interactions |
2018 |
| |
|
|
|
| Aimee Edinger |
University of California, Irvine |
Overcoming the antisense oligonucleotide delivery barrier by targeting intracellular trafficking |
2019 |
| Polly Fordyce |
Stanford University |
Leveraging high-throughput microfluidic enzyme kinetics to identify sites for allosteric manipulation |
2019 |
| Brian Liau |
Harvard University |
Interrogating the Molecular Drivers of Chemically-Induced Protein Dimerization |
2019 |
| Eric Minikel Sonia Vallabh |
The Broad Institute of Harvard and MIT |
Cell type distribution of oligonucleotide therapies in the brain |
2019 |
| Robert Spitale |
University of California, Irvine |
Expanding our understanding of PET imaging with novel probes |
2019 |
| |
|
|
|
| Michael Erb |
The Scripps Research Institute |
Cell-based ligand discovery to identify and address novel cancer targets |
2020 |
| Yamuna Krishnan |
University of Chicago |
Lysosomal Ca2+ regulation in neurodegeneration |
2020 |
| Jonathan Long |
Stanford University |
Interrogating bioactive N-acyl amino acid lipids in metabolic and neurological diseases |
2020 |
| Jason Sello |
University of California, San Francisco |
Leveraging Behavioral Profiling and Whole-Brain Imaging in Zebrafish for the Discovery and Characterization of Neuroactive Small Molecules |
2020 |
| Eranthie Weerapana Jianmin Gao |
Boston College |
Interrogating the cell-surface proteome with covalent phage libraries |
2020 |
| |
|
|
|
| Alan Saghatelian |
Salk Institute for Biological Studies |
Light Emitting Genomics (LEGO) Probes to Visualize, Capture, and Profile Rare, Transient Complexes Vital to Cellular Function |
2021 |
| Elizabeth Sattely |
Stanford University |
Covalent and non-covalent mechanisms of immune modulation by dietary small molecules |
2021 |
| Xiao Wang |
The Broad Institute of Harvard and MIT |
Harnessing chemical modifications for mRNA therapeutics |
2021 |
| |
|
|
|
| Bianxiao Cui |
Stanford University |
Discovery and therapeutic potential of a newly-discovered integrin adhesion |
2022 |
| Jarad Mason |
Harvard University |
Microporous liquids as injectable sources of oxygen |
2022 |
| Xiaoyu Zhang |
Northwestern University |
Discovering and developing antigen modifiers as new and effective cancer immunotherapeutics |
2022 |